The DUTCH Complete is their flagship test and takes hormone testing to a whole new level. This test looks at sex hormones and their metabolites, the overall diurnal pattern of free cortisol, and the total and distribution of cortisol metabolites in addition to OATs which provide insight into nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin, neuroinflammation and more.
The DUTCH Sex Hormone Metabolites is the ultimate test for HRT monitoring and great for baseline measurements as well. It is a unique method for more accurate vaginal hormone and oral progesterone monitoring. This test is run on GC-MS/MS: More accurate than LC-MS/MS or GC-MS for sex hormone metabolites!
The DUTCH Adrenal provides free cortisol patterns that parallel saliva with the addition of metabolite measurements for an improved marker for total cortisol production. This test is run on LC-MS/MS: the most accurate way to test cortisol and metabolites!
The DUTCH Plus® takes hormone testing to a whole new level. In addition to sex hormones and their metabolites, the DUTCH Complete™ looks at the overall diurnal pattern of free cortisol, and the total and distribution of cortisol metabolites. The DUTCH Plus® adds the Cortisol Awakening Response (CAR) to bring another important piece of the HPA-axis into focus.
The DUTCH Cortisol Awakening Response (CAR) (Saliva Only) test from Precision Analytical provides information about an individual's diurnal pattern of free cortisol and distribution of cortisol metabolites, which reflect the status of the neuroendocrine function of the Hypothalamic-Pituitary-Adrenal (HPA) Axis.
For some women, testing reproductive hormones (progesterone, estrogen, etc.) on a single day is sufficient. In other scenarios, the clinical picture cannot be properly captured without “mapping” out the hormonal pattern throughout their menstrual cycle.
The expected pattern of hormones shows relatively low estrogen levels early in the cycle, a surge around ovulation and modest levels in the latter third of the cycle (the luteal phase). Progesterone levels, on the other hand, stay relatively low until after ovulation. After ovulation, levels ideally increase (>10-fold) and then drop back down at the end of the cycle. A disruption in this cycle can lead to infertility or hormonal imbalance.
The DUTCH Cycle Mapping™ PLUS not only maps estrogen and progesterone through the monthly menstrual cycle, but also adds the comprehensiveness of all the hormone metabolites along with the cortisol awakening response (CAR).
Hormonal balance is key. Fluctuating levels of estradiol and progesterone play a major role in a woman’s overall health. This panel is designed for cycling women who struggle with ongoing symptoms such as monthly migraines, fertility issues, or PCOS. The addition of the cortisol awakening response (CAR), a transient, immediate rise in cortisol upon awakening (distinct from the diurnal rhythm), provides a fuller assessment of hormone fluctuations, baseline stress response, and reflects a patient’s ability to cope with anticipated challenges. CAR also shows a patient’s perception of control around chronic stress, providing insight into HPA resiliency.
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